Gastric Inhibitory Polypeptide Receptor (GIPR) (N-Term) Peptide
GIPR
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977412
Quick Overview for Gastric Inhibitory Polypeptide Receptor (GIPR) (N-Term) Peptide (ABIN977412)
Target
GIPR
(Gastric Inhibitory Polypeptide Receptor (GIPR))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- GFVLRQCGSD GQWGLWRDHT QCENPEKNEA FLDQRLILER LQVMYTVGYS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GIPR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Gastric Inhibitory Polypeptide Receptor (GIPR) peptide
GIPR Host: Synthetic BP, WB, IHC
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
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Background
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This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.
Alias Symbols: MGC126722, PGQTL2
Protein Interaction Partner: GIP,UBC
Protein Size: 466 -
Molecular Weight
- 53 kDa
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Gene ID
- 2696
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NCBI Accession
- NM_000164, NP_000155
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UniProt
- P48546
Target
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